منابع مشابه
21 years of biologically effective dose.
In 1989 the British Journal of Radiology published a review proposing the term biologically effective dose (BED), based on linear quadratic cell survival in radiobiology. It aimed to indicate quantitatively the biological effect of any radiotherapy treatment, taking account of changes in dose-per-fraction or dose rate, total dose and (the new factor) overall time. How has it done so far? Accept...
متن کاملComparison of breast sequential and simultaneous integrated boost using the biologically effective dose volume histogram (BEDVH)
PURPOSE A method is presented to radiobiologically compare sequential (SEQ) and simultaneously integrated boost (SIB) breast radiotherapy. METHODS The method is based on identically prescribed biologically effective dose (iso-BED) which was achieved by different prescribed doses due to different fractionation schemes. It is performed by converting the calculated three-dimensional dose distrib...
متن کاملApplications of the Biologically Effective Uniform Dose to Adaptive Tomotherapy and Four-dimensional Treatment Planning
The ultimate goal of radiation therapy is to efficiently deliver radiation in order to eradicate tumors, while adequately sparing nearby normal tissues. With the emergence of advanced technologies in radiation delivery, more and more conformal radiation delivery has been achieved in order to overcome challenges such as motion management between treatment fractions as well as during radiation de...
متن کاملEffective range function below threshold
We demonstrate that the kernel of the Lippmann-Schwinger equation, associated with interactions consisting of a sum of the Coulomb plus a short range nuclear potential, below threshold becomes degenerate. Taking advantage of this fact, we present a simple method of calculating the effective range function for negative energies. This may be useful in practice since the effective range expansion ...
متن کاملBiologically effective dose in fractionated molecular radiotherapy--application to treatment of neuroblastoma with (131)I-mIBG.
In this work, the biologically effective dose (BED) is investigated for fractionated molecular radiotherapy (MRT). A formula for the Lea-Catcheside G-factor is derived which takes the possibility of combinations of sub-lethal damage due to radiation from different administrations of activity into account. In contrast to the previous formula, the new G-factor has an explicit dependence on the ti...
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ژورنال
عنوان ژورنال: Deutsches Aerzteblatt Online
سال: 2019
ISSN: 1866-0452
DOI: 10.3238/arztebl.2019.0009c